Antidepressant Use in Chronic Pain Management

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Use in chronic pain management

Discussion The mind, emotions and attention play an important role in the experience of pain. In patients with chronic pain, stress, fear and depression can amplify the perception of pain. Mind-body approaches act to change a person’s mental or emotional state or utilise physical movement to train attention or produce mental relaxation. They are occasionally used as a sole treatment, but more c...

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Use of oral ketamine in chronic pain management: a review.

The analgesic effect of ketamine is primarily based on the antagonism of the N-methyl-d-aspartate (NMDA) receptor. Activation of NMDA receptors may play a crucial role in the pathogenesis of chronic pain. Little formal research has been performed on the efficacy and safety of ketamine in chronic pain, especially concerning long-term oral administration. This review provides an overview of the a...

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Compined pain self-management and antidepressant therapy are effective in patients with chronic musculoskeletal pain with depression.

Question: Does a combination of pain self-management and antidepressant therapy improve pain and depression in people with musculoskeletal pain and depression? Design: Randomised, controlled trial with concealed allocation and blinded outcome assessment. Setting: Six primary care clinics and five tertiary outpatient clinics in the USA. Participants: Primary care patients were eligible if they h...

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The use of cannabis for management of chronic pain.

The term “chronic benign pain” contains a contradiction in terms. If chronic pain is debilitating enough to compel patients to seek medical relief, then it is hardly benign. Chronic “idiopathic” pain is an equally problematic term. It implicates whatmedicine cannot explain, not that the pain is not there. Explanation or not, chronic pain patients besiege American medicine, with a recent study e...

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Rational use of opioids for management of chronic nonterminal pain.

Opioid prescribing for chronic nonterminal pain has increased in recent years, although evidence for its long-term effectiveness is weak and its potential for harm is significant. Nonmedical use of prescription opioids, diversion, and overdose deaths have also increased sharply, sparking concern about the safety of these medications. Physicians considering initiation or continuation of opioid t...

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ژورنال

عنوان ژورنال: The Primary Care Companion to The Journal of Clinical Psychiatry

سال: 2003

ISSN: 1523-5998

DOI: 10.4088/pcc.v05n0303